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The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures.One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training.This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features* All surgical techniques have been revised and updated* A new section on anesthesia and post-operative care has been included* Presents new techniques, particularly cannulation Preclinical experimental models of drug metabolism and Abstract Drug discovery and development involve the utilization of in vitro and in vivo experimental models Different models ranging from test tube experiments to Cryptorchidism Treatment & Management: Medical Therapy Cryptorchidism is the most common genital problem encountered in pediatrics Cryptorchidism literally means hidden or obscure testis and generally refers Former athlete Sophie Cape says 'experimental' surgery Former athlete Sophie Cape says 'experimental' surgery crushed Olympic hopes and left her scarred Adhesion Prevention Efficacy of Composite Meshes Parietex Int J Med Sci 2016; 13(12):936-941 doi:107150/ijms16215 Research Paper Adhesion Prevention Efficacy of Composite Meshes Parietex Proceed and 4DryField International Journal of Clinical and Experimental International Journal of Clinical and Experimental Medicine Wenjun Xia Xiaopeng Lan Ji Lv Jun Ma Wenbin Chen Ling Gao Qinghua Xia: Valproic acid (VPA Experimental orthotopic transplantation of a tissue Patients with oesophageal diseases may require surgical removal and replacement of the oesophagus Experimental osteoporosis- different methods of Abstract Rats are currently principal laboratory animals used to investigate osteoporosis The aim of the study was to present and compare two operative methods of Journal of Neurological Sciences-turkish Which is More Important for Surgical Indication? Radiology or Physical Examination: A Case Report brahim Burak ATCIOkan TRKVeysel ANTARHakan YILMAZMehmet Original Article Comparative study on induction and Int J Clin Exp Med 2015;8(6):9403-9411 ijcemcom /ISSN:1940-5901/IJCEM0008415 Original Article Comparative study on induction and effects of Experimental Models in Liver Surgery InTechOpen Experimental Models in Liver Surgery By MB Jimnez-Castro M Elias-Mir A Casillas-Ramrez and C Peralta DOI: 105772/51829
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